In vertebrates, including humans, a ductless vascular gland, located in the left upper abdomen near the stomach, which destroys old red blood cells, removes debris from the bloodstream, acts as a reservoir of blood, and produces lymphocytes.
From Middle English splene, splen, from Anglo-Norman espleen and Old French esplein, esplen, from Latin splēn, from Ancient Greek σπλήν. lien. Partially displaced the native English term milt.
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