From Middle English rinen, from Old English hrīnan, from Proto-West Germanic *hrīnan, from Proto-Germanic *hrīnaną, from Proto-Indo-European *krey-.
From Middle English rune, from Old English ryne ("a course, run, running, orbit, a flow, flux, period of time, cycle, luster, expanse, extent"), from Proto-Germanic *runiz ("course"), from Proto-Indo-European *er(e)- ("to cause to move, grow"). Cognate with German Ronne ("a channel"), Icelandic ryne ("a flow, stream"). See runnel.