Possibly a or a . An element of sound symbolism is clearly involved: compare such phonetically and semantically similar words as glop, gop, blob, clump and clod. (Still, globe, clump and clod may be related via the Proto-Indo-European root *gel-; compare clew.)
In the biological sense, proposed by Bevil R. Conway and Doris Y. Tsao, by analogy with the cytochrome-oxidase "blobs" of V1, an earlier stage in the hierarchical elaboration of colour.
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