devastate

Meaning

To ruin many or all things over a large area, such as most or all buildings of a city, or cities of a region, or trees of a forest.
To destroy a whole collection of related ideas, beliefs, and strongly held opinions.
To break beyond recovery or repair so that the only options are abandonment or the clearing away of useless remains (if any) and starting over.
To greatly demoralize, to cause to suffer intense grief or dismay

From Latin dēvastātus, perfect passive participle of dēvastō, from dē- (augmentative prefix) + vastō.

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