Darzens halogenation

Meaning

Noun

• The chemical synthesis of alkyl halides from alcohols via the treatment upon reflux of a large excess of thionyl chloride or bromide (SOX₂) in the presence of a small amount of a nitrogen base, such as a tertiary amine or pyridine or its corresponding hydrochloride or hydrobromide salt.

Origin

• Discovered in 1911 by Auguste George Darzens.